Page modified at: 09/01/2011
Pelvic Ultrasound Scan
Mid pregnancy losses can sometimes be due to abnormalities of the shape of the uterine cavity , fibroids or synechiae (adhesions) which can be identified on a pelvic ultrasound scan.
Day 2-6 FSH and LH to exclude Polycystic Ovarian Syndrome (PCOS) HbA1C to exclude diabetes Thyroid function tests Chromosomes (patient and partner) DRVVT to exclude Lupus Anticoagulant (repeated twice at least 6 weeks apart) Anticardiolipin Antibodies (repeated twice at least 6 weeks apart)
Factor V Leiden, Prothrombin Mutation Analysis, Protein S, Protein C, Activated Protein C Resistance (APCR), Anti-Thrombin III.
Endometrial Biopsy for Natural Killer Cells (NK Cells)
High levels of NK cells can be identified by an endometrial biopsy.
A speculum examination is performed to visualise the cervic A fine plastic tube is passed into the uterine cavity and a small sample of the lining (endometrium) is taken The procedure takes about 5 minnutes and is as uncomfortable as having a smear It is usually done around day 24-26 of the cycle ie just before a period Results are usually reported in about 2 weeks